Publications

Evaluating the contribution of transition state destabilization to changes in the residence time of triazole-based InhA inhibitors

Spagnuolo, L.A.; Eltschkner, S.; Yu, W.; Daryaee, F.; Davoodi, S.; Knudson, S.E.; Allen, E.K.H.; Merino, J.; Pschibul, A.; Moree, B.; Thivalapill, N.; Truglio, J.J.; Salafsky, J.; Slayden, R.A.; Kisker, C. and Tonge, P.J.; Journal of the American Chemical Society. (2017).

Second-harmonic phase determination by real-time in situ interferometry

Clancy, B. and Salafsky, J. Physical Chemistry Chemical Physics. 19, 3722-3728 (2017).

ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis

Ma, B.; Marcotte, D.; Paramasivam, M.; Michelsen, K.; Wang, T.; Bertolotti-Ciarlet, A.; Jones, J.H.; Moree, B.; Butko, M.; Salafsky, J.; Sun, X.; McKee, T. and Silvian, L.F. PLoS ONE 11 e0165983 (2016).

Detection of ligand-induced conformational changes in oligonucleotides by second-harmonic generation at a supported lipid bilayer interface

Butko, M.T; Moree, B.; Mortensen, R.B. and Salafsky, J. Analytical Chemistry. 88 (21), pp 10482–10489 (2016).

Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric Alpha-Synuclein and Reduce its Aggregation in Cells

Moree, B.; Yin G.; Lázaro, D.F.; Munari, F.; Strohäker, T.; Giller, K.; Becker, S.; Outeiro, T.F.; Zweckstetter, M. and Salafsky, J. The Journal of Biological Chemistry. 290, 27582 – 27593 (2015).

Protein Conformational Changes Are Detected and Resolved Site Specifically by Second-Harmonic Generation

Moree, B.; Connell, K.; Mortensen, R.B.; Liu, C.T.; Benkovic, S.J. and Salafsky, J. Biophysical Journal. 109, 806 – 815 (2015). 

A second-harmonic-active unnatural amino acid as a structural probe of biomolecules on surfaces

Salafsky, J.S and Cohen, B. A. The Journal of Physical Chemistry B. 112, 15103 – 15107 (2008).

Second-harmonic generation for studying structural motion of biological molecules in real time and space

Salafsky, J.S. Physical Chemistry Chemical Physics. 9, 5704 – 5711 (2007).

Detection of protein conformational change by optical second-harmonic generation

Salafsky, J.S. The Journal of Chemical Physics. 125, 074701 (2006).

Second-harmonic generation as a probe of conformational change in molecules

Salafsky, J.S. Chemical Physics Letters. 381, 705 – 709 (2003).