Biodesy’s technology directly and dynamically measures protein conformational change in high throughput. Our vision is to help transform our understanding of how proteins work, by enabling the study of all relevant interactions of dynamic, functional proteins.
The use of structural information in protein analysis has been limited by cost and throughput. Understanding function of a single protein requires the testing of many interactions and conditions. SHG is easily amenable to high throughput, and the Biodesy Delta system enables the large scale experiments required to test and map those interactions. In some cases, protein availability is also limited. Biodesy Delta requires less than 1 µg of protein per measurement, which is substantially less than existing structural techniques. By using less protein per experiment, the Biodesy Delta can enable more conditions to be studied.